Study Of the Effect of a Mixture of Extracts of Medicinal Plants on the State of the Gastric Mucosa in Gastropathy Induced by Indomethacin

Authors

  • Z.Z.Khakimov Doctor of Medical Sciences, Professor of the Department of Pharmacology of the Tashkent Medical Academy
  • G.Yu. Djanaev Doctoral student (PhD) of the Department of Pharmacology of the Tashkent Medical Academy 3Assistant, Department of Biomedical Sciences, KIUT
  • Askarov O.O Assistant, Department of Biomedical Sciences, KIUT

Keywords:

NSAIDs, indomethacin, gastropathy, gastric mucosa

Abstract

In experimental animals, on the model of indomethacin-induced gastropathy, the influence of Lesbohol on the number of erosive-destructive lesions of the gastric mucosa was studied. It has been established that Lesbohol significantly reduces the number of point, strip-like and round lesions of the gastric mucosa. At the same time, Lesbohol surpasses the well-known gastroprotector misoprostol in its activity. It is believed that the mechanism of the gastroprotective activity of Lesbohol is due to the strengthening of the protective barrier of the gastric mucosa, as a result of the suppression of the intensity of free radical processes.

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Published

2023-04-14

How to Cite

Z.Z.Khakimov, G.Yu. Djanaev, & Askarov O.O. (2023). Study Of the Effect of a Mixture of Extracts of Medicinal Plants on the State of the Gastric Mucosa in Gastropathy Induced by Indomethacin. Zeta Repository, 19, 90–95. Retrieved from https://zetarepo.com/index.php/zr/article/view/2017

Issue

Vol. 19 (2023): EMRP

Section

Articles